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Nicotinamide mononucleotide CAS#1094-61-7
Iupac Name：[(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate
CAS No.: 1094-61-7
Molecular Weight：334.221
Introduction:
Nicotinamide mononucleotide (C11H15N2O8P) is a biochemical compound and a key intermediate in nucleotide metabolism. It appears as a white to off-white crystalline powder at room temperature, is odorless, and is typically stable under ambient conditions. Structurally, it belongs to the class of ribonucleotides, specifically a pyridine-containing nucleotide derivative, formed by the linkage of nicotinamide, ribose, and a phosphate group. As such, it is categorized as both a biochemical compound and a carboxylic acid derivative due to the amide functionality in its nicotinamide moiety.
CAS No.: 1094-61-7
Molecular Weight：334.221
Introduction:
Nicotinamide mononucleotide (C11H15N2O8P) is a biochemical compound and a key intermediate in nucleotide metabolism. It appears as a white to off-white crystalline powder at room temperature, is odorless, and is typically stable under ambient conditions. Structurally, it belongs to the class of ribonucleotides, specifically a pyridine-containing nucleotide derivative, formed by the linkage of nicotinamide, ribose, and a phosphate group. As such, it is categorized as both a biochemical compound and a carboxylic acid derivative due to the amide functionality in its nicotinamide moiety.
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PRODUCT DESCRIPTION
Use and Manufacturing
3.1 UsageA product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.
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