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L-Tryptophan CAS#73-22-3

L-Tryptophan CAS#73-22-3
Iupac Name:(2S)-2-amino-3-(1H-indol-3-yl)propanoic acid
CAS No.: 73-22-3
Molecular Weight:204.22518
Introduction:
L-Tryptophan (C11H12N2O2) is a biochemical compound and a specific type of amino acid derivative. It is an essential α-amino acid containing an indole functional group, making it a key precursor in the biosynthesis of neurotransmitters such as serotonin and melatonin. At room temperature, L-tryptophan typically appears as a white to off-white crystalline solid, is odorless, and exhibits limited solubility in water, although its solubility increases in acidic or basic environments.

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PRODUCT DESCRIPTION

PropertyValue
Density1.4±0.1 g/cm³
Boiling Point447.9±35.0 °C at 760 mmHg
Melting Point289-290 °C (dec.)(lit.)
Molecular FormulaC₁₁H₁₂N₂O₂
Molecular Weight204.23
Flash Point224.7±25.9 °C
Exact Mass204.089874
PSA79.11000
LogP1.04
Vapour Pressure0.0±1.1 mmHg at 25°C
Index of Refraction1.698
InChIKeyQIVBCDIJIAJPQS-VIFPVBQESA-N
SMILESNC(Cc1c[nH]c2ccccc12)C(=O)O

Use and Manufacturing

3.1 DefinitionChEBI: The L-enantiomer of tryptophan.

3.2 General DescriptionWhite powder with a flat taste. An essential amino acid; occurs in isomeric forms.

3.3 Purification MethodsCrystallise L-tryptophan from H2O/EtOH, wash it with anhydrous diethyl ether and dry it at room temperature in a vacuum over P2O5. It sublimes at 220-230o/0.03mm with 99% recovery and unracemised [Gross & Gradsky J Am Chem Soc 77 1678 1955]. [Cox & King Org Synth Coll Vol II 612 1943, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2316-2345 1961, Beilstein 22 IV 6765.] L-Tryptophan Preparation Products And Raw materials Preparation Products

3.4 Usageadrenergic agonist

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